Perspectives in Cancer Prevention-Translational Cancer Research

1.Nutrition in Cancer: Evidence Based Nutrition Recommendations in Cancer Patients and Survivors.- 2.Tumor Stem Cell Enrichment by Anticancer Drugs: A Potential Mechanism of Tumor Recurrence.- 3. Curcumin: A potent candidate to be evaluated as a chemosensitizer in paclitaxel chemotherapy against cervical cancer.- 4. Azadirachta indica (Neem) and Neem Limonoids as Anticancer Agents: Molecular Mechanisms and Targets.- 5. In vitro studies on the antioxidant/antigenotoxic potential of aqueous fraction from Anthocephalus cadamba bark.- 6. Possible involvement of Signal Transducer and Activator of Transcription-3 (STAT3) Signaling Pathway in the Initiation and Progression of Hepatocellular Carcinoma.- 7. Simple Sequence Repeats In 5' and 3' flanking sequences of Cell Cycle Genes.- 8.Mechanisms of Chemopreventive Activity of Sulforaphane.- 9. Reciprocal relationship between VE-cadherin and Matrixmetalloproteinase expression in Endothelial cells and its Implications to Angiogenesis.- 10. Androgen receptor expression in human thyroid cancer tissues: a potential mechanism underlying the gender bias in the incidence of thyroid cancers.- 11.Novel co-ordination complexes of a few essential trace metals: Cytotoxic properties and lead identification for drug development for cancer.- 12.Why Gallbladder Cancer is common in Gangetic Belt?.- 13. Stress & Cancer Risk: The Possible Role of Work Stress.

Prof. P .R Sudhakaran is a well-known biochemist who has made significant contribution in the area of vascular biology. His major areas of research include cell matrix interaction and cell signalling in both physiological and pathological conditions including atherosclerosis, angiogenesis and cancer. As Head of the Department of Biochemistry, University of Kerala Thiruvananthapuram, and the founder Dean of School of Biological Sciences, Central University of Kerala, Kasargod, India , he has contributed significantly to biochemical education in the country and is presently the Director, Kerala State Biotechnology Commission. Dr Sudhakaran has published over 130 original research articles in international journals and is a fellow of the National Academy of Medical Sciences (India).

Prof. M. Radhakrishna Pillai is a well-known cancer biologist, Director of the Rajiv Gandhi Centre for Biotechnology, National Research Institute of the Government of India in Thiruvananthapuram, Kerala . A fellow of both the Science and Medical academies of India and the Royal College of Pathologists, London, Professor Pillai has provided one of the most elaborate data bases of cellular and molecular processes occurring during epithelial tumor progression especially roles of human papilloma virus and apoptosis. His work on cellular manifestations of HPV infection particularly p53 gene inactivation, defective apoptosis and angiogenesis culminated in the description of a "condemned mucosa syndrome", which was well received in the scientific community. He has also demonstrated the existence of various HPV 16 subtypes showing how they are associated with various grades of cervical disease.

Prof. Oommen's research contributions on comparative endocrinology in non-mammalian vertebrates led to establish identical pattern in these vertebrates as in homeotherms A new species (Gegeneophis primus) of caecilian and an extensive taxonomic revision of a hitherto poorly known rainforest caecilian