Handbook of Tuberculosis, 3 Vols.
(Sprache: Englisch)
Coinciding with the first TB therapies to enter clinical trials in 60 years, this is the most comprehensive account of the latest developments in clinical, therapeutic and basic research into the disease, presented by the most prolific of all researchers in...
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Coinciding with the first TB therapies to enter clinical trials in 60 years, this is the most comprehensive account of the latest developments in clinical, therapeutic and basic research into the disease, presented by the most prolific of all researchers in the field.Divided into three clearly structured volumes, the first deals with molecular biology and biochemistry of the pathogen, including genetics and genomics, as well as drug design. The second volume covers cell biology, immunology and vaccine development, while the third is devoted to epidemiology and clinical approaches, including drug resistance, veterinary aspects and clinical field trials.With one new infection worldwide every second, this is an essential reference for bacteriologists, immunologists, pathologists and pathophysiologists, molecular and cell biologists, as well as those working in the pharmaceutical industry.
Inhaltsverzeichnis zu „Handbook of Tuberculosis, 3 Vols. “
VOLUME 1: MOLECULAR BIOLOGY AND BIOCHEMISTRYTuberculosis - Molecular Genetics and Biochemistry: IntroductionBiochemistry of the Cell WallGlycolipids and Polyketides of M. tuberculosisPhysiology of M. tuberculosisNutrient TransportIron Uptake by M. tuberculosisProtein TransportPE and PPE Gene Family Members in M. tuberculosisVirulence/Persistence Mechanisms of M. tuberculosisGenomicsTranscriptomics and Transcriptional RegulationProteomics of M. tuberculosisStructureMolecular Mechanisms of Dormancy and ResuscitationM. tuberculosis in the PhagosomeMolecular Mechanisms of Drug Resistance of M. tuberculosisExperimental Genetics of M. tuberculosisMolecular Evolution of MycobacteriaVOLUME 2: IMMUNOLOGY AND CELL BIOLOGYIntroduction: Immunity to M. tuberculosis and BCGRecognition Receptors and Phagocytosis for M. tuberculosisTranscriptional Response of Macrophages and Dendritic Cells to M. tuberculosisDendritic Cells and Antigen PresentationKilling Mechanisms of the Host Against M. tuberculosisManipulation of the Macrophage ResponseConventional T Cells and their Antigenic RepertoireUnconventional T CellsCytokines in TuberculosisAntibodies in TuberculosisPathologyMaintenance of Latent Infection with Correlates of Protective ImmunityGenetics of Resistance (mouse and man)HIV/TB InteractionsNovel Vaccination Strategies Against TuberculosisExperimental Animal Models of TuberculosisVOLUME 3: CLINICS DIAGNOSTICS THERAPY AND EPIDEMIOLOGYClinics Diagnostics Therapy Epidemiology: IntroductionGlobal Epidemiology of TuberculosisSurveillance Studies and InterpretationMolecular Epidemiology of M. tuberculosisDiagnosis of M. tuberculosis: ClinicalClinical Disease (with and without HIV)Management of Tuberculosis PatientsChemotherapyNew Drugs and Clinical Drug TrialsLatencyDrug Resistance in Clinical ContextNovel Drug Treatment Strategies - Co-infectionsModelingBCG Vaccination
Autoren-Porträt
Prof. Dr. Stefan H.E. Kaufmann is Founding Director of the Max Planck Institute for Infection Biology, Berlin. He has published more than 600 scientific articles and is member of numerous scientific societies and committees e.g. current President of the European Federation of Immunological Societies, and Chair of the Immunology division of the American Society of Microbiology. He has won numerous prestigious awards including the Scientific Prize of Smith Kline Beecham and the Pettenkofer Prize.Paul van Helden is Professor of Medical Biochemistry at Stellenbosch University, South Africa. He is Director of Laboratory Research for the Desmond Tutu TB Centre. He is a past president of the SA Society of Biochemistry and Molecular Biology, and has received the Gold medal of this society.Eric Rubin is Professor of Immunology and Infectious Diseases at the Harvard School of Public Health. He carried out both his MD and PhD work at Tufts University.Warwick Britton is Professor of Medicine at the University of Sydney, Australia. He serves as Chairman of the State Committee for the Australian Society of Clinical Immunology and Allergy.
Bibliographische Angaben
- 2007, 1350 Seiten, 60 farbige Abbildungen, Maße: 17,8 x 24,6 cm, Gebunden, Englisch
- Herausgegeben: Stefan H. E. Kaufmann, Paul van Helden, Eric Rubin
- Verlag: Wiley-VCH
- ISBN-10: 3527316833
- ISBN-13: 9783527316830
Sprache:
Englisch
Pressezitat
"...Edited and written by the leading experts in the field [this three volume handbook] is the most comprehensive book on this topic available..." -Anticancer Research
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