Handbook of Sepsis

PART 1. SEPSIS: AN OVERVIEW:.-1. What is sepsis?.- 2. The epidemiology of sepsis.- PART 2. THE PATHOGENESIS OF SEPSIS:.- 3.The pathogenesis.- 4.The coagulation system in sepsis.-5.The endocrine system in sepsis.- 6.Biomarkers for sepsis.- PART 3.SEPSIS MANAGEMENT:.- 7.International clinical practice guidelines.- 8.  Fluids.- 9.Vasopressors.- 10. Multiorgan failure.- 11.Importance of the pathogen.- 12.Antimicrobial therapy.- 13.Adjunctive immunotherapy.- PART IV. SEPSIS IN THE COMING DECADE:.- 14.Novel trial design in sepsis.- 15. Sepsis in low- and middle income countries.- 16 Sepsis: the road ahead.

Dr. Wiersinga is Professor of Medicine and chief of the Division of Infectious Diseases at the Department of Internal Medicine, Academic Medical Center, Amsterdam. In addition, he serves as clinical lecturer for biomedical science and medicine studies, and Principal Investigator at the Center for Experimental Molecular Medicine (CEMM), University of Amsterdam. His research centers on the pathogenesis of sepsis with a special interest in pneumonia, melioidosis and the gut microbiome. He is member of several guidelines on the management of patients with pneumonia and sepsis. Parameters of esteem include the ESCMID Young Investigator Award, the O'Callaghan PhD award and the Australian and New Zealand Intensive Care Society (ANZICS) Intensive Care Global Rising Star Award. He coordinates the EU Marie Curie ITN European Sepsis Academy.

"The purpose is to help both clinicians and laboratory scientists better understand the pathogenesis of sepsis and its management. This is a worthy goal and this book meets its objective of clearly explaining this complex topic. ... This is a high-quality resource that does an excellent job of simplifying a complex topic. It is a valuable resource for professionals/practitioners and anyone who desires to study sepsis in depth." (John M Horne, Doody's Book Reviews, March, 2019)
"This book provides the reader with the context on which sepsis care has been built, a review of current management, as well as a discussion of future trends. It would be a welcomed addition to a bookshelf of any trainee, health professional, or basic/clinical researcher who seek to immerse themselves into this complex and well-studied disease entity. It is concise and lends itself as an excellent, yet intimate, introduction into this vast topic area." (Vatsal Trivedi and Manoj M. Lalu, Anesthesia & Analgesia, Vol. 128 (2), February, 2019)

"Encompassing 16 chapters and 267 pages, the Handbook of Sepsis provides an up-to-date overview of the enigmatic clinical syndrome of sepsis. ... Asides from the text itself, clearly labelled colour diagrams and figures aid the process of learning, and well-defined tables are also interspersed throughout the book which can be referred to independently, without interrupting the flow of the main script." (Ned Gilbert-Kawai, British Journal of Hospital Medicine, Vol. 79 (7), July, 2018)