DNA-Pharmaceuticals
Formulation and Delivery in Gene Therapy and DNA Vaccination
(Sprache: Englisch)
With its focus on a completely novel class of pharmaceuticals, this book collates the hitherto scarce literature about DNA drug formulation keenly desired by biotechnologists, molecular biologists and pharmacists, as well as those working in the...
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Klappentext zu „DNA-Pharmaceuticals “
With its focus on a completely novel class of pharmaceuticals, this book collates the hitherto scarce literature about DNA drug formulation keenly desired by biotechnologists, molecular biologists and pharmacists, as well as those working in the biotechnological and pharmaceutical industries.As such, this volume presents a wide range of gene delivery systems needed for different therapeutic applications. It fills the gap between research and clinical trials and describes pharmaceutical fundamentals for the development of efficient DNA pharmaceuticals.
Inhaltsverzeichnis zu „DNA-Pharmaceuticals “
PrefaceDNA Vaccines: an OverviewDNA as a Pharmaceutical: Regulatory AspectsFrom Bulk to Delivery: Plasmid Manufacturing and DeliveryMinimized, CpG-Depleted and Methylated DNA Vectors: Towards Perfection in Nonviral Gene TherapyLocalized Nucleic Acid Delivery: a Discussion of Selected MethodsDNA Needle InjectionNeedleless Jet Injection of Naked DNA von Nonviral in vivo Gene TransferPlasmid Inhalation: Delivery to the AirwaysHydrodynamic Gene DeliveryDNA Pharmaceuticals for Skin DiseasesElectrotransfection: an OverviewElectrogenetransfer in Clinical ApplicationsCancer Inhibition in Mice after Systematic Application of Plasmid Driven Expression of Small Interfering RNAsIndex
Autoren-Porträt
Dr. Martin Schleef studied Biology at the Universities of Würzburg and Bielefeld, Germany and holds a PhD from the University of Bielefeld.Martin Schleef received post-doctoral training from the Institut Pasteur Paris, France. He joined QIAGEN GmbH, Hilden, Germany in 1994 and is co-founder and CEO of PlasmidFactory in Bielefeld since 2000.
Bibliographische Angaben
- 2005, XXII, 253 Seiten, 6 farbige Abbildungen, 31 Schwarz-Weiß-Abbildungen, Maße: 17,9 x 24,6 cm, Gebunden, Englisch
- Herausgegeben: Martin Schleef
- Verlag: Wiley-VCH
- ISBN-10: 3527311874
- ISBN-13: 9783527311873
- Erscheinungsdatum: 25.08.2005
Sprache:
Englisch
Rezension zu „DNA-Pharmaceuticals “
"Eine sehr interessante und umfassende Sammlung zum Wirkstoff DNA und eine ideale Ergänzung zu den "Plasmids for Therapy and Vaccination"."Pharmazie in unserer Zeit"Mit diesem Buch wurde der aktuelle Stand der Forschung zu DNA-Pharmazeutika zusammengetragen und den unterschiedlichen Aspekten von der Herstellung bis hin zur Applikation Rechnung getragen. Führende Wissenschaftlerinnen und Wissenschaftler haben an dem Buch mitgewirkt, das in das Regal jedes Forschers gehört, der sich mit der zukunftsweisenden Thematik auseinandersetzt."Arzneimittel-Forschung / Drug Research
Pressezitat
"It makes a valuable contribution to an important, topical and rapidly growing area of research and will be useful and of interest to students and professors, specialists and beginners in the field. I recommend it strongly, to libraries and individual researchers, in areas ranging all the way from biological chemistry to medicine." ChemMedChem
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