Cachexia and Wasting

Anatomy, Historical Perspective and Epidemiology.- Functional Anatomy of the 'Adipose Organ'.- Body Silhouette and Body Fat Distribution.- Historic Views on Cachexia in Humans with Special Reference to Cardiac Cachexia.- Epidemiology of Cachexia.- Biochemistry, Physiology and 'Clinics' of Adipose Tissue.- Energy Values of Foods.- Diet-Induced Thermogenesis.- Assessment of Nutritional Status.- Biochemical Parameters of Nutrition.- Nitrogen Balance and Protein Requirements: Definition and Measurements.- Plasma Proteins and Protein Catabolism.- Nutritional Status Assessment.- Immunological Parameters of Nutrition.- Functional Parameters of Nutrition.- The Different Features of Wasting in Humans.- Anorexia.- Starvation: Social, Voluntary, and Involuntary Causes of Weight Loss.- Cachexia Related to Multiple Causes.- Non-AIDS Lipodystrophy Syndrome.- Pathophysiology of Wasting/Cachexia.- Body Composition: Physiology, Pathophysiology and Methods of Evaluation.- Protein Metabolism in Cachexia.- Lipid Metabolism in Cachexia.- Glucose Metabolism.- Cytokines in Cachexia.- Cytokines in Chronic Inflammation.- Biochemistry of the Growth Hormone-Releasing Peptides, Secretagogues and Ghrelin.- Ghrelin as a New Factor in the Central Network Controlling Appetite and Food Intake.- Leptin and Des-acyl Ghrelin: Their Role in Physiological Body Weight Regulation and in the Pathological State.- Brain Mechanisms in Wasting and Cachexia.- Body Weight Regulation and Hypothalamic Neuropeptides.- Medical Causes of Wasting/Cachexia.- Diabetes.- Endocrine Disorders.- Psychiatric Diseases and Depression.- Cachexia in Chronic Kidney Disease: Malnutrition-Inflammation Complex and Reverse Epidemiology.- Gastrointestinal Diseases.- Chronic Obstructive Pulmonary Disease (COPD) and Treatment of COPD-Related Cachexia.- Cachexia in Cardiovascular Illness.- Cachexia and Ageing.- Epidemiology of Malnutrition in the Elderly.- Pathophysiology of Body Composition Changes in Elderly People.- The

Professor Mantovani is Full Professor of Medical Oncology and Chief of the Division and Laboratory of Medical Oncology at University of Cagliari, School of Medicine, Cagliari, Italy. His research interests include treatment of cancer-related anorexia/cachexia and oxidative stress, combined-modality therapy of human cancers and cancer immunotherapy. He is first author of more than 200 publications in top-rated cancer journals. Many colleagues from all over the world are acting as co-editors.