Antidepressants, Antipsychotics, Anxiolytics

ANTIDEPRESSANTS

Introduction to Depression and Bipolar Disorders

Trends in Treatment and Prevention

Marketed Drugs:

-tricyclic/tetracyclic antidepressants, adrenergic agents, serotonergic agents, dopaminergic agents, GABAergic agents, MAO inhibitors (partial list)

Drugs under Development:

-serotonin reuptake inhibitors, PDE inhibitors, CCH-releasing factors, melatonine products, AMPAkines, Substance-P antagonists (partial list)

ANTIANXIOLYTICS

Introduction to Anxiety

Opportunities for Drug Intervention

Marketed Drugs:

- bezodiazepines, serotonergic drugs, GABAergic agents, dopaminergic agents, serotonin reuptake stimulants (partial list)

Drugs under Development:

- beta-carbolines, MAO inhibitors, 5-HT receptor antagonists, CCH-releasing factors, neurokinin ligands, melatonin agonists (partial list)

ANTIPSYCHOTICS

Introduction to schizophrenia and other psychoses

Opportunities for Drug Intervention

Marketed Drugs:

- typical antipsychotics, atypical APs with dopaminergic and serotonergic activity (partial list)

Drugs under Development:

- AMPAkines, COMT inhibitors, tachykinin antagonists, anticholinergic agents, natural products and herbal remedies (partial list)

MEDICINES FOR ATTENTION DEFICIT / HYPERACTIVITY DISORDER (ADHD)

Facts about ADHD

Marketed Drugs:

- psychostimulants, antidepressants

Drugs under Development:

- psychostimulants, antidepressants, AMPA receptor modulators, natural products and herbal remedies

Future of ADHD Therapy

The editors all work for the Spanish-based pharmaceutical company Esteve, a world leader in neuropharmaceuticals.

Helmut Buschmann is the research director of Esteve, in charge of the discovery and development of new active substances for a variety of neurological disorders. He was formerly the head of research at Gruenenthal, a Germany-based pharma company that also specialized in neuropharmaceuticals. During his time at Gruenenthal, he published a widely acclaimed book on analgesics that pioneered the integrated approach followed also in his most recent book.