Amyloid Proteins

Preparation of Pure Populations of Amyloid-beta Protein Oligomers of Defined Size.- Preparation of Well-Defined and Stable beta-Barrel Pore-Forming Amyloid-beta42 Oligomers.- Unveiling Brain Abeta Heterogeneity through Targeted Proteomic Analysis.- Preparation of -Synuclein Amyloid Assemblies for Toxicity Experiments.- Generation and Characterization of Stable -Synuclein Oligomers.- In Vitro Analysis of -Synuclein Amyloid Formation and Cross-Reactivity.- Preparation of Tau Oligomers after Protein Extraction from Bacteria and Brain Cortices.- Purification and Characterization of Low-n Tau Oligomers.- Preparation and Characterization of Tau Oligomer Strains.- Purification and Fibrillation of Recombinant Human Amyloid-beta, Prion Protein and Tau under Native Conditions.- Preparation of Amyloidogenic  Aggregates from EF-Hand beta -parvalbumin and S100 Proteins.- Kinetic Analysis of Amyloid Formation.- Mapping Amyloid Regions in Gad m 1with Peptide Arrays.- Non-Invasive Structural Analysis of Intermediate Species during Fibrillation: An Application of Small-Angle X-Ray Scattering.- Analysis of Covalent Modifications of Amyloidogenic Proteins using Two-Dimensional Electrophoresis: Prion Protein and Its Sialylation.- Amplification and Detection of Minuscule Amounts of Misfolded Prion Protein by Using The Real-Time Quaking-Induced-Conversion.- Bacterial Amyloids.- Addressing Intracellular Amyloidosis in Bacteria with RepA-WH1, a Prion-Like Protein.- Study of Amyloids Using Yeast.- Neurotoxic Ca2+ Signaling Induced by Amyloid-beta Oligomers in Aged Hippocampal Neurons In Vitro.- Preparation and Culturing of Human Primary Vascular Cells.- Live Imaging of Pathological Tau Protein and Tau Antibodies in a Human Neuron-Like Cellular Model.- Effects of Amyloid-beta Peptide on the Biology of Human Neural Stem Cells.- Development of Mouse Monoclonal Antibodies