Allergy Frontiers:Clinical Manifestations

Allergic Rhinitis and Conjunctivitis: Update on Pathophysiology.- Allergic Conjunctivitis: Update on Its Pathophysiology and Perspectives for Future Treatment.- Non-allergic Rhinitis.- Nasal Polyposis: A Model of Chronic Airways Inflammation.- The Nonallergic Rhinitis of Chronic Fatigue Syndrome.- Epigenetics Chapter: The Role of Allergy in Chronic Rhinosinusitis.- Otitis Media and Sinusitis.- Allergic Rhinitis, Asthma, and Obstructive Sleep Apnea: The Link.- Common Colds and Respiratory Viruses: Impact on Allergy and Asthma.- Cold, Dry Air, and Hyperosmolar Challenges in Rhinitis.- Mechanisms of Mucus Induction in Asthma.- Mechanisms of Cough in Asthma and Allergic Airway Disease.- Airway Hyperresponsiveness: Inflammatory Mechanisms and Clinical Aspects.- Mechanisms of Nocturnal Asthma.- Severe Asthma in Adults: Pathology to Clinical Aspects.- Exercise-Induced Asthma: Clinical Manifestations.- Aspirin-Sensitive Asthma.- Airway Remodeling in Asthma and Therapeutic Implications.- Occupational Asthma and Its Relationship to Occupational Rhinitis.- Non-atopic Asthma: A Continuing Enigma.- Asthma in the Athlete.- Allergic Bronchopulmonary Aspergillosis.- Mechanisms of Anaphylaxis.- Drug Hypersensitivity: Clinical Manifestations and Diagnosis.- Immunological Principles of Drug Hypersensitivity.- Food Allergy: Mechanisms and Clinical Manifestations.- Lactose and Fructose Intolerance.- Insect Sting Allergy in Adults.- Fungal Allergy as Yet Unsolved.- Latex Allergy: Clinical Manifestations.

Prof. Stephen Holgate, MRC Clinical Professor of Immunopharmacology, Division of Respiratory Cell and Molecular Biology, University of Southhampton School of Medicine. Applying basic science to the clinical interface in allergy and asthma has been the guiding principle of Prof. Stephen Holgate's career. This has involved him in environmental and genetic epidemiology, physiology, cell and molecular biology of disease processes as they occur in humans. An AAAAI member since 1986 and Fellow from 1993, Professor Holgate has been active in the field of allergy and immunology both in the United Kingdom and overseas and in 2001 received the Academy's Honorary Fellow Award. He was President of the British Society of Allergy and Clinical Immunology (BSACI) from 1990-93 and the Robert Cook Memorial Lecturer in 1995 and 2000. He received the RCP London Graham Bull Prize for research and was elected an honorary member of the Association of Physicians in UK and Ireland following the delivery of the Sir William Osler Lecture in 2003. He has been an active contributor to the Collegium Internationale Allergologicum since 1990. Professor Holgate is a member of the Infection, Inflammation and Repair Division in the School of Medicine, University of Southampton at Southampton General Hospital, UK and since 1987 has held a Medical Research Council (MRC) Clinical Professorship. He received his undergraduate medical training at Charing Cross Hospital, London and specialised in respiratory medicine and allergy. He holds Fellowships from the Royal Colleges of Physicians, Pathologists, Institute of Biology and Academy of Medical Sciences. He is a member of the Royal Commission on Environmental Pollution and has been a censor of the Royal College of Physicians. He has served on a number of Government Committees including the Sub-committee for Efficacy and Adverse Drug Reactions of the CSM (SEAR), MRC Project Grant Committee, Systems Board, Cross Board Group and most recently Councils

From the reviews:

"Allergy Frontiers is a remarkable undertaking by 3 well-known experts in the field of allergy/immunology. ... Clinical Manifestations, contains 500 pages and comprises 30 chapters that summarize the current knowledge of the clinical manifestations of allergic diseases ... . helpful to clinicians, who are often challenged to understand why some patients respond to treatment and others do not. ... will serve as an invaluable resource for academicians, allergy/immunology training programs, and curious individuals who require more than a basic understanding of the subject." (Katherine Gundling, Journal of the American Medical Association, Vol. 302 (17), November, 2009)